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Chemistry Contact

Department Chair:

Petar Dvornic

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Contact Person:
Linda Hoesli

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Phone: 620-235-4748
Fax: 620-235-4003

Chemistry Department
101 Heckert-Wells
Pittsburg State University
1701 South Broadway
Pittsburg KS 66762

Department of Chemistry Seminars

Fall 2017 - Spring 2018

October 13, 2017
Tendai Gadzikwa, Department of Chemistry, Kansas State University, Manhattan, Kansas
Metal-organic framework (MOF) materials are microporous, crystalline solids that have found application in the areas of separation, sequestration, detection, and catalysis, among many others.1 Possessing pores of small-molecule sized dimensions, and composed of organic ligands that are highly tailorable,2 MOF-based catalysts are particularly attractive targets for use in selective transformations.3 This presentation will detail recent progress in assembling multifunctionalizable MOF materials, with the eventual goal of constructing enzyme-inspired MOF catalysts. continue reading>>

December 1, 2017
Mark Fisher, Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas
Title:  Bacterial toxin entry into cells: A Trojan Horse Story.
This lecture will focus on the molecular mechanisms of anthrax toxin entry into cells.  In order to understand this mechanism, the structure of the main transport system will be examined in light of data collected from our laboratory and our collaborators.  The success of this transport system relies on acidification of the endosome which in turn results in a massive unfolding/refolding process enabling lethal toxin transport through and across membranes.  This acidification process is exploited by anthrax as well as other numerous toxin and viral systems to gain entry into the cell.  I will also present our strategy for developing novel anti-toxin small molecule prophylactic approaches based on blunting acid depend transitions. continue reading>>